Gupta S, Lemenze A, Donnelly RJ, Connell ND, Kadouri DE. Res Microbiol. Keeping it together: absence of genetic variation and DNA incorporation by the predatory bacteria Micavibrio aeruginosavorus and Bdellovibrio bacteriovorus during predation.
Iacona JR, Monteleone NJ, Lemenze AD, Cornett AL, Lutz CS. Transcriptomic studies provide insights into the tumor suppressive role of miR-146a-5p in non-small cell lung cancer (NSCLC) cells. RNA Biol. 2019 Dec;16(12):1721-1732. doi: 10.1080/15476286.2019.1657351. Epub 2019 Aug 23.
Wang X, Perryman AL, Li SG, Paget SD, Stratton TP, Lemenze A, Olson AJ, Ekins S, Kumar P, Freundlich JS. Intrabacterial Metabolism Obscures the Successful Prediction of an InhA Inhibitor of Mycobacterium tuberculosis. ACS Infect Dis. 2019 Dec 13;5(12):2148-2163. doi: 10.1021/acsinfecdis.9b00295. Epub 2019 Nov 5
Eaton, W.D., McGee, K.M., Donnelly, R.H., Lemenze, A., Karas, O., & Hajibabaei, M. (2019). Differences in the soil microbial community and carbon‐use efficiency following development of Vochysia guatemalensis tree plantations in unproductive pastures in Costa Rica.
Inclan-Rico J.M., Hernandez C.M., Henry E.K., Federman H.G., Sy C.B., Ponessa J.J., Lemenze A.D., Joseph N., Soteropoulos P., Beaulieu A.M., Yap G.S., & Siracusa M.C. Trichinella spiralis-induced mastocytosis and erythropoiesis are simultaneously supported by a bipotent mast cell/erythrocyte precursor cell. PLoS Pathog. 2020;16(5):e1008579. Published 2020 May 18.
Inclan-Rico J.M, Ponessa J.J, Valero-Pacheco N, Hernandez C, Sy C.B, Lemenze A.D, Beaulieu A.M, Siracusa M.C. Basophils prime group 2 innate lymphoid cells for neuropeptide-mediated inhibition. Nat Immunol (2020). https://doi.org/10.1038/s41590-020-0753-y Published 2020 August 17.
Perlman BE, Merriam A, Lemenze AD, Begum S, Zhao Q, Shawber CJ, Douglas NC. Hypoxia Induces Trophoblast Migration and Invasion Gene Pathways a Subset of which are Reduced in Preeclampsia CVS. Fertility and Sterility. 2020;114(3):E339-E340. Published 2020 Sept 01.
Panayotova G, Lemenze AD, Minze LJ, Aware N, Nguyen CT, Graviss EA, Ghobrial M, Guarrera JV, Lunsford KE. HDysregulation of Wnt Canonical Signaling Portends Pre-Transplant Immune Dysfunction and Post-Transplant Morbidity and Mortality in Liver Transplant Recipients. Transplantation and Tissue Engineering. 2020;231(34):E221. Published 2020 Oct 01.
Fei Chen, Darine W. El Naccache, John Ponessa, Alexander Lemenze, Vanessa Espinosa, Wenhui Wu, Katherine Lothstein, Linhua Jin, Amariliz Rivera, Mark Siracusa, William C. Gause. Monocyte-derived alveolar macrophages mediate resistance to migrating helminths through depletion of arginine availability. bioRxiv 2020.10.02.322388; doi: https://doi.org/10.1101/2020.10.02.322388
Yin T, Yao W, Lemenze AD, D'Adamio L. Danish and British dementia ITM2b/BRI2 mutations reduce BRI2 protein stability and impair glutamatergic synaptic transmission. J Biol Chem. 2020 Nov 10:jbc.RA120.015679. doi: 10.1074/jbc.RA120.015679
Eaton, W.D.; McGee, K.M.; Hoke, E.; Lemenze, A.; Hajibabaei, M. Influence of Two Important Leguminous Trees on Their Soil Microbiomes and Nitrogen Cycle Activities in a Primary and Recovering Secondary Forest in the Northern Zone of Costa Rica. Soil Syst. 2020, 4, 65.
Dong X, Antao OQ, Song W, Sanchez GM, Zembrzuski K, Koumpouras F, Lemenze A, Craft J, Weinstein JS. Type I Interferon-Activated STAT4 Regulation of Follicular Helper T Cell-Dependent Cytokine and Immunoglobulin Production in Lupus. Arthritis Rheumatol. 2021 Mar;73(3):478-489. doi: 10.1002/art.41532. Epub 2021 Jan 29. PMID: 33512094; PMCID: PMC7914134.
Eaton WD, McGee KM, Donnelly R, Lemenze A, Larimer M, Hajibabaei M. The impacts of a logging road on the soil microbial communities, and carbon and nitrogen components in a Northern Zone Costa Rican forest. Applied Soil Ecology, Volume 164, 2021, 103937, ISSN 0929-1393, https://doi.org/10.1016/j.apsoil.2021.103937.
Perlman BE, Merriam AA, Lemenze A, Zhao Q, Begum S, Nair M, Wu T, Wapner RJ, Kitajewski JK, Shawber CJ, Douglas NC. Implications for Preeclampsia: Hypoxia-Induced Notch Promotes Trophoblast Migration. Reproduction. 2021 Mar 1:REP-20-0483.R1. doi: 10.1530/REP-20-0483. Epub ahead of print. PMID: 33784241.
Song, Wenzhi and Antao, Olivia Q. and Condiff, Emily and Sanchez, Gina M. and Chernova, Irene and Zembrzuski, Krzysztof and Steach, Holly and Rubtsova, Kira and Lemenze, Alexander and Laidlaw, Brian J. and Craft, Joseph and Weinstein, Jason, Development of Tbet- and CD11c-Expressing B Cells in a Viral Infection Requires T Follicular Helper Cells Outside of Germinal Centers. Available at SSRN: https://ssrn.com/abstract=3825161 or http://dx.doi.org/10.2139/ssrn.3825161
Alison E Obr, PhD, Alexander Lemenze, PhD, Krystopher Maingrette, MS, Virginia Ciliento, PhD, Yun-juan Chang, PhD, Joseph J Bulatowicz, MS, Teresa L Wood, PhD, A Frame-Shift for IGF-1R in Breast Cancer and Metastasis, Journal of the Endocrine Society, Volume 5, Issue Supplement_1, April-May 2021, Pages A1009–A1010, https://doi.org/10.1210/jendso/bvab048.2065
Sones JL, Yarborough CC, O’Besso V, Lemenze A, Douglas NC (2021) Genotypic analysis of the female BPH/5 mouse, a model of superimposed preeclampsia. PLoS ONE 16(7): e0253453. https://doi.org/10.1371/journal.pone.0253453
Hu MD, Golovchenko NB, Burns GL, Nair PM, Kelly TJ 4th, Agos J, Irani MZ, Soh WS, Zeglinski MR, Lemenze A, Bonder EM, Sandrock I, Prinz I, Granville DJ, Keely S, Watson AJM, Edelblum KL. γδ Intraepithelial Lymphocytes Facilitate Pathological Epithelial Cell Shedding Via CD103-Mediated Granzyme Release. Gastroenterology. 2021 Dec 1:S0016-5085(21)03804-X. doi: 10.1053/j.gastro.2021.11.028. Epub ahead of print. PMID: 34861219.
Fei Chen, Darine W. El-Naccache, John J. Ponessa, Alexander Lemenze, Vanessa Espinosa, Wenhui Wu, Katherine Lothstein, Linhua Jin, Olivia Antao, Jason S. Weinstein, Payal Damani-Yokota, Kamal Khanna, Peter J. Murray, Amariliz Rivera, Mark C. Siracusa, William C. Gause, Helminth resistance is mediated by differential activation of recruited monocyte-derived alveolar macrophages and arginine depletion, Cell Reports, Volume 38, Issue 2, 2022, 110215, ISSN 2211-1247, https://doi.org/10.1016/j.celrep.2021.110215.
Rossi M, Aspromonte SM, Kohlhapp FJ, Newman JH, Lemenze A, Pepe RJ, DeFina SM, Herzog NL, Donnelly R, Kuzel TM, Reiser J, Guevara-Patino JA, Zloza A. Gut Microbial Shifts Indicate Melanoma Presence and Bacterial Interactions in a Murine Model. Diagnostics. 2022; 12(4):958. https://doi.org/10.3390/diagnostics12040958
Jia L, Wu G, Alonso S, Zhao C, Lemenze A, Lam YY, Zhao L, Edelblum KL. A transmissible γδ intraepithelial lymphocyte hyperproliferative phenotype is associated with the intestinal microbiota and confers protection against acute infection. Mucosal Immunol. 2022 May 19. doi: 10.1038/s41385-022-00522-x. PMID: 35589986.
Lemenze A, Mittal N, Perryman A, Daher S, Ekins S, Occi J, Ahn Y, Wang X, Russo R, Patel J, Daugherty R, Wood D, Connell N, Freundlich J. Rickettsia Aglow: A Fluorescence Assay and Machine Learning Model to Identify Inhibitors of Intracellular Infection. ACS Infectious Diseases. 2022; https://doi.org/10.1021/acsinfecdis.2c00014
El-Naccache D, Chen F, Palma M, Lemenze A, Fischer M, Wu W, Mishra P, Eltzschig H, Robson S, Virgilio F, Yap G, Edelblum K, Hasko G, Gause W. Adenosine metabolized from extracellular ATP promotes type 2 immunity through triggering A2BAR signaling in intestinal epithelial cells. Cell Reports. 2022; https://doi.org/10.1016/j.celrep.2022.111150
Peng J, Sy CB, Ponessa JJ, Lemenze AD, Hernandez CM, Inclan-Rico JM, Siracusa MC (2022). Monocytes maintain central nervous system homeostasis following helminth-induced inflammation. Proceedings of the National Academy of Sciences, 119(37), e2201645119. doi:10.1073/pnas.2201645119
Fung H, Teryek M, Lemenze AD, Bergsbaken T (2022). CD103 fate mapping reveals that intestinal CD103 tissue-resident memory T cells are the primary responders to secondary infection. Science Immunology, 7(77):eabl9925. doi: 10.1126/sciimmunol.abl9925
Chitale P, Lemenze AD, Fogarty EC, Shah A, Grady C, Odom-Mabey A, Johnson WE, Yang J, Eren AM, Brosch R, Kumar P, Alland D (2022). A comprehensive update to the Mycobacterium tuberculosis H37Rv reference genome. Nature Communications 13, 7068. doi:10.1038/s41467-022-34853-x
Helen Y. Fung, Angie M. Espinal, Matthew Teryek, Alexander D. Lemenze, Tessa Bergsbaken, STAT4 increases the phenotypic and functional heterogeneity of intestinal tissue-resident memory T cells, Mucosal Immunology, 2023. ISSN 1933-0219 https://doi.org/10.1016/j.mucimm.2023.03.002.
Zhao Q, Larios K, Naaldijk Y, Sherman L, Chemerinski A, Okereke K, Rameshwar P, Lemenze A, Douglas NC, Morelli SS. Mesenchymal Stem Cell Secretome Alters Gene Expression and Upregulates Motility of Human Endometrial Stromal Cells. Reproduction. 2023 May 1:REP-22-0485. doi: 10.1530/REP-22-0485. PMID: 37252830.
N. Kalkota, A Lemenze, A Babwah, N Douglas, Endometrial Adhesion G Protein-Coupled Receptors are differentially expressed across the menstrual cycle and early mouse pregnancy, Fertility and Sterility, 2023. https://doi.org/10.1016/j.fertnstert.2023.05.113
Xu C, Wang A, Ebraham L, Sullivan L, Tasker C, Pizutelli V, Couret J, Hernandez C, Kolli P, Deb PQ, Fritzky L, Subbian S, Gao N, Lo Y, Salvatore M, Rivera A, Lemenze A, Fitzgerald-Bocarsly P, Tyagi S, Lu W, Beaulieu A, Chang TL. Interferon ɛ restricts Zika virus infection in the female reproductive tract. PNAS Nexus. 2023 Oct 25;2(11):pgad350. doi: 10.1093/pnasnexus/pgad350. PMID: 37954158; PMCID: PMC10639110.
Eaton W, Hamilton D, Chen W, Lemenze A, Soteropoulos PP. Genetic identification of potential nodulating bacteria and nodule-associated bacteria (NAB) within root nodules of Inga punctata trees in a Costa Rican Cloud Forest. Research Square; 2023. DOI: 10.21203/rs.3.rs-3767521/v1.
Eaton, W.D., Hamilton, D.A., Lemenze, A. and Soteropoulos, P. (2024), Natural regeneration or tree planting in a tropical forest-to-pasture damaged area: which is more efficacious for soil ecosystem recovery?. Restor Ecol e14127. https://doi.org/10.1111/rec.14127
Anat Chemerinski, May Shen, Nuriban Valero-Pacheco, Qingshi Zhao, Trystn Murphy, Lea George, Alex Lemenze, Lauren Sherman, Debra Heller, Xiaowei Chen, Tracy Wu, Peter G McGovern, Sara S Morelli, Ripla Arora, Aimee M Beaulieu, Nataki C Douglas, The impact of ovarian stimulation on the human endometrial microenvironment, Human Reproduction, 2024;, deae048, https://doi.org/10.1093/humrep/deae048
William D. Eaton, Debra A. Hamilton, Wen Chen, Alexander Lemenze, Patricia Soteropoulos. Use of high throughput DNA analysis to characterize the nodule-associated bacterial community from four ages of Inga punctata trees in a Costa Rican cloud forest[J]. AIMS Microbiology, 2024, 10(3): 572-595. doi: 10.3934/microbiol.2024027
Hu WT, Kaluzova M, Dawson A, Sotelo V, Papas J, Lemenze A, Shu C, Jomartin M, Nayyar A, Hussain S. Clinical and CSF single-cell profiling of post-COVID-19 cognitive impairment. Cell Rep Med. 2024 May 21;5(5):101561. doi: 10.1016/j.xcrm.2024.101561. Epub 2024 May 13. PMID: 38744274; PMCID: PMC11148803.
Lothstein KE, Chen F, Mishra P, Smyth DJ, Wu W, Lemenze A, Kumamoto Y, Maizels RM, Gause WC. Helminth protein enhances wound healing by inhibiting fibrosis and promoting tissue regeneration. Life Sci Alliance. 2024 Aug 23;7(11):e202302249. doi: 10.26508/lsa.202302249. PMID: 39179288; PMCID: PMC11342954.
Joseph, J.; Premeaux, T.A.; Tandon, R.; Murphy, E.L.; Bruhn, R.; Nicot, C.; Herrera, B.B.; Lemenze, A.; Alatrash, R.; Baffour Tonto, P.; et al. Dendritic Cells Pulsed with HAM/TSP Exosomes Sensitize CD4 T Cells to Enhance HTLV-1 Infection, Induce Helper T-Cell Polarization, and Decrease Cytotoxic T-Cell Response. Viruses 2024, 16, 1443. https://doi.org/10.3390/v16091443
Wang K, Espinosa V, Wang Y, Lemenze A, Kumamoto Y, Xue C, Rivera A.0.Innate cells and STAT1-dependent signals orchestrate vaccine-induced protection against invasive Cryptococcus infection. mBio0:e01944-24.https://doi.org/10.1128/mbio.01944-24
Peignier A, Kim J, Lemenze A, Parker D (2024) Monocyte-regulated interleukin 12 production drives clearance of Staphylococcus aureus. PLOS Pathogens 20(10): e1012648. https://doi.org/10.1371/journal.ppat.1012648
Gungor Aydin, A., Lemenze, A. & Bieszczad, K.M. Functional diversities within neurons and astrocytes in the adult rat auditory cortex revealed by single-nucleus RNA sequencing. Sci Rep 14, 25314 (2024). https://doi.org/10.1038/s41598-024-74732-7
Daiyong Deng, Habeebunnisa Begum, Tong Liu, Jiangyan Zhang, Qiang Zhang, Ting-yu Chu, Hong Li, Alexander Lemenze, Mainul Hoque, Patricia Soteropoulos, Pingping Hou; NFAT5 governs cellular plasticity-driven resistance to KRAS-targeted therapy in pancreatic cancer. J Exp Med 4 November 2024; 221 (11): e20240766. doi: https://doi.org/10.1084/jem.20240766
Sanchez GM, Hirsch ES, VanValkenburg A, Mayer DP, Gbedande K, Francis RL, Song W, Antao OQ, Brimmer KE, Lemenze A, Stephens R, Johnson WE, Weinstein JS. Aberrant zonal recycling of germinal center B cells impairs appropriate selection in lupus. Cell Rep. 2024 Nov 10;43(11):114978. doi: 10.1016/j.celrep.2024.114978. 39527476.
Talk at Merck Deep Sequencing Forum 2018, Boston, MA
Talk at ABRF 2017, San Diego, California